Pharma, Pharmaceutics and Biotechnology Conference

Pharmacokinetics and pharmacodynamics are two of the major important areas in pharmacology that explain how drugs interact with the body, hence how the body affects drugs. Pharmacokinetics deals with how drugs are distributed within the body absorbed, metabolized, distributed, and excreted while pharmacodynamics describes what drugs do to the body.PK/PD knowledge is indispensable in attaining an optimal position for drug therapy, especially for the treatment of infectious diseases.

For infections, drugs should be applied with the right concentration at the site of infection without becoming toxic and lethal to pathogens. The PK data will allow the scientists to predict at what rate the drug goes to the blood. Thus, after following a certain rate of absorption, they can predict how much concentration of the drug would be favorable for therapeutic purposes. Then the PD data will weight out the potency and effectiveness at such a concentration.

This makes PK/PD modeling an absolute approach toward the development of antibiotics, antivirals, or other antimicrobial therapies for infectious diseases.PK/PD can, for example be used to select antibiotic therapy to determine the best dosing scheme which would give maximum bacterial killing with minimal induction of antimicrobial resistance.

Patients' factors, age, weight and organ function will thus necessitate appropriate adjustments in this personalized approach to therapy. It will bring out the very important interaction of pharmacokinetics and pharmacodynamics aspects in the treatment of infectious diseases.

Attendees would learn how PK/PD modeling impacts and affects drug development at all stages, dosing strategies, as well as fighting against drug resistance.

The discussion will throw light upon recent advances in the understanding of drug dynamics and, as a result, the impact of the same upon the efficacy and safety of antimicrobial therapies.