Pharma, Pharmaceutics and Biotechnology Conference

Novel drug delivery systems: Advanced and innovative methodology in pharmaceutical science to improve the current technologies of drug delivery regarding effectiveness and safety.

This session covers new breakthroughs in NDDS and their impact on the bioavailability of drugs, targeted delivery, and treatment compliance.

The conventional route of drug delivery has many limitations, for example, poor solubility, rapid metabolism, and unsatisfactory therapeutic effects. In this respect, NDDS aims at overcoming these limitations through advanced approaches to enhance the pharmacokinetics and pharmacodynamics of therapeutic agents. Of these new technologies, we have nanoparticles, liposomes, and micro needles.

Over the last few years, much attention has been drawn upon nanoparticles inasmuch as they can encapsulate drugs and release them in a controlled manner. Such carriers can also be engineered to target tissues or cells for localized therapy and minimal systemic side effects.

For instance, targeted delivery of chemotherapeutic drugs to cancer cells will significantly enhance therapeutic efficacy while causing minimal damage to normal tissues. Another promising drug delivery system is the liposomes, which are lipid bilayers that can enclose drugs so as to provide a protective covering against degradation and release under controlled conditions.

It has also been used to achieve better bioavailability of poorly soluble drugs and targeted delivery to predefined sites in the body, such as a tumor or tissues with inflammation.

Micro needles are essentially minimally invasive drug-delivery systems capable of delivering vaccines and therapeutic agents transcutaneous. The approach does not only improve patient compliance but also enhances the pharmacokinetics of certain drugs by bypassing first-pass metabolism. Moreover, smart drug delivery systems are becoming a reality, revolutionizing this field as well.

This can sense physiological stimuli such as pH and temperature variations and release the drug on demand at the target site. This dynamic approach to drug delivery theoretically maximizes therapeutic effects while minimizing side effects. In this scenario, the integration of these newer drug delivery systems into clinical practice would be a step forward in the domain of pharmacotherapy.

It will give an overview of the most recent developments in the field of NDDS, such as their roles in bettering the efficacy and safety of drugs and the patient adherence to the course for a session.

Insight into future directions in drug delivery technologies will empower the participants with the knowledge serving as the base for contribution appropriately towards an ever-changing landscape of pharmaceutical research and development.