The definition of Immunotoxicology, according to the World Health Organization, encompasses the study on environmental toxins, drugs, and infectious agents that cause a sudden effect on the immunity. It plays a very key role in understanding how a pathogen - such as bacteria, viruses, and parasites - interacts with the immune system while sometimes compromising it.
In infectious diseases, immunotoxicology study ranges from the level of reaction of the immune system to the particular pathogens to the toxic effects of certain drugs that are used to combat infections. Such pathogens may provide exaggerated immune responses and cause infections that can be as devastating as septic shock while others can avoid the response altogether to cause chronic infections.
Immunotoxicology provides answers to such mechanisms by shedding some light on why such dreadful pathogens are so potent and why the immune system cannot respond in a more adequate manner. Drug-induced immunotoxicity is one of the areas of concern within immunotoxicology. Drugs that are intended to fight infections can cause harm in the form of impaired immune responses.
The action of some chemotherapeutics, antivirals, and certain antibiotics may inhibit the function of the immune system or cause hypersensitivity as a result, secondary immune dysfunction becomes permanent.
Immunotoxicology research also encompasses effects from immunosuppressive drugs-even though these are often required for patients possessing transplants or suffering from autoimmune disorders-they leave the patient open to opportunistic infections.
Immunotoxicology is, therefore, also of paramount importance in the development of immunomodulation therapies that are towards attempting to either argument an immune response or modulate excessive inflammation that arises in conditions like that associated with HIV and COVID-19.The session would focus on the interaction of immunotoxicology with infectious diseases, with a focus on pathogen-induced impairment of immunity and drug-induced immunotoxicity problems.
Discussion during the meeting will focus on how to reverse immunoharm in these settings, such as creating targeted therapies balancing infection control needs with preserving the host immune system.