Pharma, Pharmaceutics and Biotechnology Conference

Pharmacodynamics the study of drug interaction with biologic systems, hence a constituent branch of pharmacology. Advanced concepts in mechanisms of drug action, dose-response relationship, and implications of these concepts for therapeutic strategies and drug development will be presented in this session.

At the very heart of pharmacodynamics lies the principle that drugs act on the body through interaction related to specific receptors, such that interactions with drugs are normally agonist in nature.

The session shall also consider the different kinds of receptors-G-protein-coupled, ion channels and enzyme-linked, and how these interactions translate into therapeutic effects.

The major principle of pharmacodynamics is the dose-response relationship, which basically reflects that, for any type of effect of a drug, increases in drug concentration lead to increases in the magnitude of the drug effect up to a certain point.

It is basic in determining an acceptable dosing regimen that will most effectively provide the desired therapeutic effect with minimal adverse impact. Among other matters to be included are efficacy, potency, and the therapeutic index, which determines the relative safety of a drug by comparing the effective dose for a given criterion to the toxic dose for the same criterion.

A very critical area of pharmacodynamics is interaction pharmacological by additive, synergistic, and antagonistic effects when using two or more drugs combined. It all lies in this optimization of combination therapies and protection against adverse interaction in patients.

During this lecture, real examples of drug interactions and their implications in practice will be presented. Another related issue the evaluation of signaling pathway activity gives an answer to is to determine which of these pathways are activated by drug-receptor interaction since this might serve as a clue for understanding further the mechanism of drug action.

The following chapter provides information on some of the most important pathways MAPK/ERK and PI3K/act, with their role in mediating the impact of some therapeutic agents.

Pharmacodynamics is such a field of study from where enlightened subjects would be enlightened regarding recent developments in the fields, such as the advances in the molecular basis of drug action, and the development of new drugs on specific pathways of treatment.

A deep understanding of principles would assist healthcare practitioners formulate tailored plans of therapy for maximum benefits without side effects.

This session will provide a comprehensive overview of pharmacodynamics, taking into account the highly important role that this area plays in drug development and clinical practice.

By the end of the session, attendees will be well-equipped to leave with considerably greater insight into how drugs interact within biological systems and, hence, with new insights into how this knowledge can improve care for patients.